所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)氯(lv)(lv)化劑(ji)(ji)選(xuan)自氯(lv)(lv)化亞砜(feng)、五氯(lv)(lv)化磷、三氯(lv)(lv)氧磷和(he)(he)三氯(lv)(lv)化磷中(zhong)(zhong)(zhong)的(de)(de)(de)(de)一種或(huo)幾種。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)氯(lv)(lv)化劑(ji)(ji)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)摩爾(er)比(bi)為(wei)(wei)2～：1。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)氯(lv)(lv)化劑(ji)(ji)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)摩爾(er)比(bi)為(wei)(wei)：1、2：1或(huo)：1。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)溶(rong)劑(ji)(ji)選(xuan)自甲苯和(he)(he)/或(huo)二(er)氯(lv)(lv)乙烷(wan)。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)溶(rong)劑(ji)(ji)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)質(zhi)量(liang)(liang)比(bi)為(wei)(wei)4～5：1。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)溶(rong)劑(ji)(ji)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)質(zhi)量(liang)(liang)比(bi)為(wei)(wei)4：1或(huo)5：1。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)回流(liu)反(fan)應(ying)后(hou)(hou)，還(huan)包括：降(jiang)(jiang)溫(wen)。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)降(jiang)(jiang)溫(wen)后(hou)(hou)的(de)(de)(de)(de)溫(wen)度(du)為(wei)(wei)20～30℃。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)降(jiang)(jiang)溫(wen)后(hou)(hou)的(de)(de)(de)(de)溫(wen)度(du)為(wei)(wei)25℃、30℃或(huo)20℃。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)降(jiang)(jiang)溫(wen)后(hou)(hou)，還(huan)包括加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)、過濾和(he)(he)烘干。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)的(de)(de)(de)(de)加(jia)(jia)水(shui)(shui)時間(jian)(jian)(jian)為(wei)(wei)30min～60min。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)時間(jian)(jian)(jian)為(wei)(wei)30min。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)加(jia)(jia)入的(de)(de)(de)(de)水(shui)(shui)量(liang)(liang)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)質(zhi)量(liang)(liang)比(bi)為(wei)(wei)1～：1。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)加(jia)(jia)入的(de)(de)(de)(de)水(shui)(shui)量(liang)(liang)與所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)中(zhong)(zhong)(zhong)間(jian)(jian)(jian)體的(de)(de)(de)(de)質(zhi)量(liang)(liang)比(bi)為(wei)(wei)1：1。在(zai)(zai)本(ben)(ben)發(fa)(fa)(fa)明(ming)的(de)(de)(de)(de)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)中(zhong)(zhong)(zhong)的(de)(de)(de)(de)攪(jiao)拌(ban)(ban)時間(jian)(jian)(jian)為(wei)(wei)～1h。在(zai)(zai)某(mou)(mou)(mou)(mou)些實(shi)(shi)(shi)(shi)施(shi)(shi)(shi)(shi)(shi)(shi)(shi)例(li)(li)中(zhong)(zhong)(zhong)，所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)加(jia)(jia)水(shui)(shui)攪(jiao)拌(ban)(ban)中(zhong)(zhong)(zhong)的(de)(de)(de)(de)攪(jiao)拌(ban)(ban)時間(jian)(jian)(jian)為(wei)(wei)。本(ben)(ben)發(fa)(fa)(fa)明(ming)對所(suo)(suo)(suo)述(shu)(shu)(shu)(shu)(shu)(shu)(shu)(shu)過濾和(he)(he)烘干的(de)(de)(de)(de)方法并無特殊的(de)(de)(de)(de)限制。國內4-吡啶丙(bing)醇高純度(du)優(you)級品量(liang)(liang)大從優(you)。鹽城(cheng)環保吡啶丙(bing)醇供應(ying)

所(suo)得(de)水(shui)(shui)合物、晶(jing)(jing)型(xing)與(yu)實施例(li)1中(zhong)α晶(jing)(jing)型(xing)一致。實施例(li)6將10g西他沙星(xing)()、4g富馬酸(suan)(，)、200ml乙醇(chun)和(he)50ml水(shui)(shui)加(jia)(jia)入到500ml反應(ying)瓶，加(jia)(jia)熱(re)(re)(re)(re)至(zhi)(zhi)40℃以上，攪拌(ban)(ban)(ban)反應(ying)1～2小時(shi)(shi)，冰水(shui)(shui)浴降(jiang)溫(wen)(wen)(wen)攪拌(ban)(ban)(ban)析(xi)晶(jing)(jing)2～5小時(shi)(shi)，抽濾(lv)洗滌(di)，40～60℃真(zhen)(zhen)空干(gan)燥(zao)4～6小時(shi)(shi)，得(de)到類白色(se)粉(fen)末狀固體(ti)，收率90％，hplc純度％。根(gen)據x-射線粉(fen)末衍射、x-射線單晶(jing)(jing)衍射、差(cha)熱(re)(re)(re)(re)分(fen)析(xi)和(he)熱(re)(re)(re)(re)重(zhong)分(fen)析(xi)，所(suo)得(de)水(shui)(shui)合物、晶(jing)(jing)型(xing)與(yu)實施例(li)1中(zhong)α晶(jing)(jing)型(xing)一致。對比例(li)1為溶劑參照cnb中(zhong)實施例(li)1的(de)方法，取(qu)(qu)(qu)(含，北京中(zhong)碩醫藥科技開發有限公司)投入1l三(san)口瓶，加(jia)(jia)入200ml，避光條件(jian)(jian)下攪拌(ban)(ban)(ban)升(sheng)溫(wen)(wen)(wen)至(zhi)(zhi)55～60℃回流(liu)(liu)(liu)，溶清后趁(chen)熱(re)(re)(re)(re)過濾(lv)，濾(lv)液重(zhong)新(xin)加(jia)(jia)熱(re)(re)(re)(re)至(zhi)(zhi)回流(liu)(liu)(liu)。取(qu)(qu)(qu)，回流(liu)(liu)(liu)狀態(tai)下滴(di)加(jia)(jia)到反應(ying)瓶中(zhong)，滴(di)畢回流(liu)(liu)(liu)反應(ying)1h，保溫(wen)(wen)(wen)條件(jian)(jian)下加(jia)(jia)300ml正(zheng)(zheng)庚烷(wan)，析(xi)出淡(dan)黃色(se)固體(ti)，降(jiang)至(zhi)(zhi)室溫(wen)(wen)(wen)，攪拌(ban)(ban)(ban)析(xi)晶(jing)(jing)1h，過濾(lv)，濾(lv)液用少量正(zheng)(zheng)庚烷(wan)洗滌(di)，35～40℃真(zhen)(zhen)空干(gan)燥(zao)，得(de)淡(dan)黃色(se)固體(ti)a。對比例(li)2甲(jia)乙酮為溶劑參照cnb中(zhong)實施例(li)2的(de)方法，取(qu)(qu)(qu)(含)投入1l三(san)口瓶，加(jia)(jia)入200ml甲(jia)乙酮，避光條件(jian)(jian)下攪拌(ban)(ban)(ban)升(sheng)溫(wen)(wen)(wen)至(zhi)(zhi)55～60℃，溶清后趁(chen)熱(re)(re)(re)(re)過濾(lv)，濾(lv)液重(zhong)新(xin)加(jia)(jia)熱(re)(re)(re)(re)至(zhi)(zhi)回流(liu)(liu)(liu)。取(qu)(qu)(qu)，回流(liu)(liu)(liu)狀態(tai)下滴(di)加(jia)(jia)到反應(ying)瓶中(zhong)，滴(di)畢回流(liu)(liu)(liu)反應(ying)50min，保溫(wen)(wen)(wen)條件(jian)(jian)下加(jia)(jia)300ml正(zheng)(zheng)己烷(wan)，析(xi)出淡(dan)黃色(se)固體(ti)，降(jiang)至(zhi)(zhi)室溫(wen)(wen)(wen)，攪拌(ban)(ban)(ban)析(xi)晶(jing)(jing)1h，過濾(lv)，濾(lv)液用少量正(zheng)(zheng)庚烷(wan)洗滌(di)，35～40℃真(zhen)(zhen)空干(gan)燥(zao)。浙江現(xian)代吡(bi)(bi)啶丙醇(chun)怎么收費4-吡(bi)(bi)啶丙醇(chun)價格優惠的(de)廠家(jia)。

其(qi)(qi)蒸氣(qi)與空氣(qi)能形成(cheng)性(xing)(xing)的(de)混合物。極限為(wei)(wei)(體積)。屬于(yu)一(yi)種(zhong)中等(deng)危險物品(pin)(pin)。屬易燃低毒(du)物質。蒸氣(qi)的(de)毒(du)性(xing)(xing)為(wei)(wei)乙(yi)醇的(de)二倍，內(nei)服時(shi)的(de)毒(du)性(xing)(xing)相(xiang)反(fan)(fan)。圖1為(wei)(wei)異(yi)丙(bing)(bing)(bing)醇分子(zi)結構式。異(yi)丙(bing)(bing)(bing)醇在許多情(qing)況下可代(dai)替乙(yi)醇作為(wei)(wei)溶劑，是(shi)一(yi)種(zhong)良好溶劑和(he)化(hua)(hua)工(gong)原料(liao)，用(yong)于(yu)涂料(liao)、醫藥、農藥、化(hua)(hua)妝品(pin)(pin)等(deng)工(gong)業，也用(yong)于(yu)生(sheng)產(chan)、異(yi)丙(bing)(bing)(bing)酯(zhi)、異(yi)丙(bing)(bing)(bing)胺（莠去津(jin)的(de)原料(liao)）、二異(yi)丙(bing)(bing)(bing)醚(mi)、乙(yi)酸(suan)(suan)異(yi)丙(bing)(bing)(bing)酯(zhi)和(he)麝香草酚等(deng)。是(shi)石(shi)油化(hua)(hua)工(gong)發展史上(shang)從石(shi)油原料(liao)制(zhi)得(de)的(de)個化(hua)(hua)工(gong)產(chan)品(pin)(pin)。生(sheng)產(chan)工(gong)藝1855年，法(fa)(fa)國(guo)人M.貝(bei)特洛首先報道用(yong)丙(bing)(bing)(bing)烯和(he)硫(liu)(liu)酸(suan)(suan)經水(shui)(shui)(shui)(shui)合制(zhi)得(de)異(yi)丙(bing)(bing)(bing)醇，稱間接水(shui)(shui)(shui)(shui)合法(fa)(fa)。1919年，美(mei)國(guo)人C.埃利(li)斯(si)對此進(jin)(jin)行(xing)了工(gong)業開發。1920年底(di)，美(mei)國(guo)新澤西標準油公司采(cai)用(yong)埃利(li)斯(si)法(fa)(fa)建立了生(sheng)產(chan)裝置，正(zheng)式投入生(sheng)產(chan)。1951年，英國(guo)卜內(nei)門化(hua)(hua)學工(gong)業公司開始用(yong)丙(bing)(bing)(bing)烯直(zhi)接水(shui)(shui)(shui)(shui)合法(fa)(fa)生(sheng)產(chan)異(yi)丙(bing)(bing)(bing)醇。其(qi)(qi)后(hou)，各(ge)國(guo)相(xiang)繼采(cai)用(yong)此法(fa)(fa)并(bing)作了改(gai)進(jin)(jin).間接水(shui)(shui)(shui)(shui)合法(fa)(fa):丙(bing)(bing)(bing)烯與硫(liu)(liu)酸(suan)(suan)反(fan)(fan)成(cheng)硫(liu)(liu)酸(suan)(suan)氫異(yi)丙(bing)(bing)(bing)酯(zhi)，后(hou)者(zhe)經水(shui)(shui)(shui)(shui)解而成(cheng)異(yi)丙(bing)(bing)(bing)醇，反(fan)(fan)應(ying)式為(wei)(wei):CH3CH＝CH2+H2SO4─→(CH3)2CHOSO3H;(CH3)2CHOSO3H+H2O─→(CH3)2CHOH+H2SO4,所用(yong)硫(liu)(liu)酸(suan)(suan)濃(nong)度一(yi)般大于(yu)60％（質量）,反(fan)(fan)應(ying)在2～～65°C下進(jin)(jin)行(xing)；水(shui)(shui)(shui)(shui)解在稍加壓和(he)30°C以(yi)下進(jin)(jin)行(xing)。直(zhi)接水(shui)(shui)(shui)(shui)合法(fa)(fa):丙(bing)(bing)(bing)烯和(he)水(shui)(shui)(shui)(shui)在催化(hua)(hua)劑存在下加溫、加壓進(jin)(jin)行(xing)水(shui)(shui)(shui)(shui)合反(fan)(fan)應(ying)，生(sheng)成(cheng)異(yi)丙(bing)(bing)(bing)醇，選擇性(xing)(xing)為(wei)(wei)96％。

4℃）：[2]3-苯丙(bing)醇(chun)(chun)毒理(li)學數(shu)(shu)(shu)(shu)據編輯1、皮(pi)膚/眼睛刺激：兔子(zi)皮(pi)膚標準德雷茲染眼實驗：10mg/24H對皮(pi)膚有中等的刺激。2、急性毒性：大鼠(shu)經(jing)口LD50：2300mg/kg；兔子(zi)皮(pi)膚LD50：5gm/kg[2]3-苯丙(bing)醇(chun)(chun)分子(zi)結(jie)構(gou)數(shu)(shu)(shu)(shu)據編輯1、摩爾(er)(er)折射(she)率：2、摩爾(er)(er)體(ti)積（cm3/mol）：3、等張比容（）：4、表(biao)面張力（dyne/cm）：5、極(ji)化(hua)(hua)(hua)(hua)率（10-24cm3）：[2]3-苯丙(bing)醇(chun)(chun)計算化(hua)(hua)(hua)(hua)學數(shu)(shu)(shu)(shu)據編輯1.疏(shu)水參(can)數(shu)(shu)(shu)(shu)計算參(can)考值（XlogP）:無2.氫鍵供體(ti)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):13.氫鍵受(shou)體(ti)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):14.可旋轉(zhuan)化(hua)(hua)(hua)(hua)學鍵數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):35.互變異構(gou)體(ti)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):無6.拓撲分子(zi)極(ji)性表(biao)面積7.重原(yuan)子(zi)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):108.表(biao)面電荷:09.復雜度:10.同位素原(yuan)子(zi)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):011.確(que)定(ding)(ding)原(yuan)子(zi)立(li)(li)構(gou)中心(xin)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):012.不確(que)定(ding)(ding)原(yuan)子(zi)立(li)(li)構(gou)中心(xin)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):013.確(que)定(ding)(ding)化(hua)(hua)(hua)(hua)學鍵立(li)(li)構(gou)中心(xin)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):014.不確(que)定(ding)(ding)化(hua)(hua)(hua)(hua)學鍵立(li)(li)構(gou)中心(xin)數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):015.共價鍵單(dan)元數(shu)(shu)(shu)(shu)量(liang)(liang)(liang):1[2]3-苯丙(bing)醇(chun)(chun)合成方(fang)法(fa)編輯1.制備(bei)方(fang)法(fa)：由肉桂酸乙(yi)酯催化(hua)(hua)(hua)(hua)加(jia)氫制得(de)。加(jia)氫反(fan)應在高壓釜中進行(xing)，采用(yong)鉻-銅-鋇催化(hua)(hua)(hua)(hua)劑，溫(wen)度為200℃，氫壓約(yue)20MPa。加(jia)氫反(fan)應5-9h后，冷卻濾去催化(hua)(hua)(hua)(hua)劑，濾液用(yong)提取(qu)。提取(qu)液回(hui)收后進行(xing)減壓蒸餾，收集110-112℃（）餾分，即(ji)為成品，收率約(yue)85%。另一種(zhong)制法(fa)是氯(lv)芐與環氧乙(yi)烷(wan)通過格氏反(fan)應得(de)到3-苯基(ji)丙(bing)醇(chun)(chun)氯(lv)鎂鹽，再(zai)用(yong)硫酸水解(jie)得(de)到3-苯基(ji)丙(bing)醇(chun)(chun)。此法(fa)收率約(yue)65-70%。附近4-吡(bi)啶丙(bing)醇(chun)(chun)購買渠(qu)道。

所(suo)述(shu)(shu)(shu)降(jiang)溫(wen)(wen)(wen)結晶的(de)(de)(de)(de)(de)(de)(de)(de)(de)溫(wen)(wen)(wen)度(du)(du)為20～30℃。在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，所(suo)述(shu)(shu)(shu)降(jiang)溫(wen)(wen)(wen)結晶后，還(huan)包(bao)括過濾和烘干(gan)(gan)，得到(dao)(dao)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體。本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)對(dui)所(suo)述(shu)(shu)(shu)過濾和烘干(gan)(gan)的(de)(de)(de)(de)(de)(de)(de)(de)(de)方法(fa)并無特殊的(de)(de)(de)(de)(de)(de)(de)(de)(de)限制，采用(yong)本(ben)(ben)(ben)(ben)領域技術(shu)人(ren)員熟(shu)(shu)知(zhi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)過濾和烘干(gan)(gan)的(de)(de)(de)(de)(de)(de)(de)(de)(de)方法(fa)即可。本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)中(zhong)(zhong)(zhong)(zhong)，得到(dao)(dao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體具有式(ⅰ)所(suo)示(shi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)結構：本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)提供的(de)(de)(de)(de)(de)(de)(de)(de)(de)處理方法(fa)得到(dao)(dao)的(de)(de)(de)(de)(de)(de)(de)(de)(de)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體的(de)(de)(de)(de)(de)(de)(de)(de)(de)收率(lv)和純(chun)度(du)(du)較高。中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體的(de)(de)(de)(de)(de)(de)(de)(de)(de)收率(lv)高于(yu)％，純(chun)度(du)(du)高于(yu)％。得到(dao)(dao)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體后，將(jiang)所(suo)述(shu)(shu)(shu)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體與氯(lv)化(hua)劑(ji)在(zai)溶(rong)劑(ji)中(zhong)(zhong)(zhong)(zhong)進行氯(lv)化(hua)反(fan)應，得到(dao)(dao)四(si)氯(lv)吡(bi)啶酸。的(de)(de)(de)(de)(de)(de)(de)(de)(de)，具體為：將(jiang)所(suo)述(shu)(shu)(shu)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體加(jia)(jia)入溶(rong)劑(ji)中(zhong)(zhong)(zhong)(zhong)，升(sheng)溫(wen)(wen)(wen)至(zhi)85～120℃，然后滴(di)加(jia)(jia)氯(lv)化(hua)劑(ji)，滴(di)加(jia)(jia)完成后，升(sheng)溫(wen)(wen)(wen)至(zhi)回(hui)(hui)流(liu)溫(wen)(wen)(wen)度(du)(du)，回(hui)(hui)流(liu)反(fan)應2～3h后，得到(dao)(dao)四(si)氯(lv)吡(bi)啶酸。在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，將(jiang)所(suo)述(shu)(shu)(shu)中(zhong)(zhong)(zhong)(zhong)間(jian)(jian)(jian)(jian)體加(jia)(jia)入溶(rong)劑(ji)中(zhong)(zhong)(zhong)(zhong)，升(sheng)溫(wen)(wen)(wen)至(zhi)100℃、110℃、90℃、85℃。本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)對(dui)升(sheng)溫(wen)(wen)(wen)至(zhi)85～120℃的(de)(de)(de)(de)(de)(de)(de)(de)(de)升(sheng)溫(wen)(wen)(wen)速(su)率(lv)并無特殊的(de)(de)(de)(de)(de)(de)(de)(de)(de)限制，采用(yong)本(ben)(ben)(ben)(ben)領域技術(shu)人(ren)員熟(shu)(shu)知(zhi)的(de)(de)(de)(de)(de)(de)(de)(de)(de)升(sheng)溫(wen)(wen)(wen)速(su)率(lv)即可。在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，所(suo)述(shu)(shu)(shu)滴(di)加(jia)(jia)的(de)(de)(de)(de)(de)(de)(de)(de)(de)時(shi)間(jian)(jian)(jian)(jian)為～1h。在(zai)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，所(suo)述(shu)(shu)(shu)滴(di)加(jia)(jia)的(de)(de)(de)(de)(de)(de)(de)(de)(de)時(shi)間(jian)(jian)(jian)(jian)為。本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)對(dui)所(suo)述(shu)(shu)(shu)升(sheng)溫(wen)(wen)(wen)至(zhi)回(hui)(hui)流(liu)溫(wen)(wen)(wen)度(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)時(shi)間(jian)(jian)(jian)(jian)并無特殊的(de)(de)(de)(de)(de)(de)(de)(de)(de)限制，在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，所(suo)述(shu)(shu)(shu)升(sheng)溫(wen)(wen)(wen)至(zhi)回(hui)(hui)流(liu)溫(wen)(wen)(wen)度(du)(du)的(de)(de)(de)(de)(de)(de)(de)(de)(de)時(shi)間(jian)(jian)(jian)(jian)為。在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)，所(suo)述(shu)(shu)(shu)回(hui)(hui)流(liu)反(fan)應的(de)(de)(de)(de)(de)(de)(de)(de)(de)時(shi)間(jian)(jian)(jian)(jian)為、3h或(huo)2h。在(zai)本(ben)(ben)(ben)(ben)發(fa)(fa)(fa)(fa)(fa)(fa)(fa)明(ming)(ming)(ming)(ming)的(de)(de)(de)(de)(de)(de)(de)(de)(de)某(mou)些(xie)(xie)實(shi)(shi)施例(li)中(zhong)(zhong)(zhong)(zhong)。2-吡(bi)啶丙醇國內(nei)的(de)(de)(de)(de)(de)(de)(de)(de)(de)生產廠(chang)家。鎮江本(ben)(ben)(ben)(ben)地(di)吡(bi)啶丙醇工廠(chang)直銷

國內高純度(du)2-吡(bi)啶(ding)(ding)丙醇(chun)購買(mai)渠道。鹽(yan)城環保吡(bi)啶(ding)(ding)丙醇(chun)供應(ying)

從而導致(zhi)所謂(wei)“夏(xia)季煙(yan)霧(wu)(wu)”現象(xiang)，光化(hua)(hua)學(xue)煙(yan)霧(wu)(wu)會刺激人(ren)的(de)(de)眼睛和(he)(he)呼吸系統，危害(hai)人(ren)們(men)的(de)(de)身體健康和(he)(he)植(zhi)物(wu)的(de)(de)生(sheng)(sheng)(sheng)長(chang)，因(yin)此(ci)，異(yi)丙(bing)(bing)(bing)(bing)(bing)醇(chun)是(shi)一(yi)種對(dui)環(huan)境、人(ren)體均(jun)有害(hai)的(de)(de)化(hua)(hua)學(xue)品(pin)，在印刷中減少(shao)其用(yong)(yong)(yong)量是(shi)一(yi)種必然的(de)(de)趨勢。食品(pin)添加(jia)(jia)劑(ji)(ji)大(da)(da)允(yun)許(xu)使(shi)(shi)用(yong)(yong)(yong)量大(da)(da)允(yun)許(xu)殘(can)留(liu)量標準▼▲添加(jia)(jia)劑(ji)(ji)中文(wen)(wen)名稱允(yun)許(xu)使(shi)(shi)用(yong)(yong)(yong)該種添加(jia)(jia)劑(ji)(ji)的(de)(de)食品(pin)中文(wen)(wen)名稱添加(jia)(jia)劑(ji)(ji)功能大(da)(da)允(yun)許(xu)使(shi)(shi)用(yong)(yong)(yong)量（g/kg）允(yun)許(xu)殘(can)留(liu)量（g/kg）異(yi)丙(bing)(bing)(bing)(bing)(bing)醇(chun)食品(pin)食品(pin)用(yong)(yong)(yong)香(xiang)(xiang)料用(yong)(yong)(yong)于配制(zhi)香(xiang)(xiang)精的(de)(de)各(ge)香(xiang)(xiang)料成分不得超過在GB2760中的(de)(de)大(da)(da)允(yun)許(xu)使(shi)(shi)用(yong)(yong)(yong)量和(he)(he)大(da)(da)允(yun)許(xu)殘(can)留(liu)量化(hua)(hua)學(xue)性質無色透明可燃性液體，有似乙醇(chun)的(de)(de)氣(qi)味。與水、乙醇(chun)、、氯(lv)(lv)仿混溶(rong)。用(yong)(yong)(yong)途(tu)用(yong)(yong)(yong)作(zuo)(zuo)實驗用(yong)(yong)(yong)化(hua)(hua)學(xue)試(shi)劑(ji)(ji)及(ji)色譜分析試(shi)劑(ji)(ji)用(yong)(yong)(yong)途(tu)萃(cui)(cui)(cui)取(qu)(qu)溶(rong)劑(ji)(ji)，載(zai)體溶(rong)劑(ji)(ji)。GB2760-1996：暫允(yun)許(xu)使(shi)(shi)用(yong)(yong)(yong)的(de)(de)食品(pin)用(yong)(yong)(yong)香(xiang)(xiang)料。用(yong)(yong)(yong)于甜菜糖、糖果、營養增補片劑(ji)(ji)、酒花萃(cui)(cui)(cui)取(qu)(qu)、檸(ning)檬油(you)、香(xiang)(xiang)辛料油(you)樹脂、酵母(mu)等加(jia)(jia)工。用(yong)(yong)(yong)途(tu)作(zuo)(zuo)為有機原料和(he)(he)溶(rong)劑(ji)(ji)有著用(yong)(yong)(yong)途(tu)。作(zuo)(zuo)為化(hua)(hua)工原料，可生(sheng)(sheng)(sheng)產、過氧化(hua)(hua)氫、甲基異(yi)丁基酮、二(er)異(yi)丁基酮、異(yi)丙(bing)(bing)(bing)(bing)(bing)胺、異(yi)丙(bing)(bing)(bing)(bing)(bing)醚(mi)、異(yi)丙(bing)(bing)(bing)(bing)(bing)醇(chun)醚(mi)、異(yi)丙(bing)(bing)(bing)(bing)(bing)基氯(lv)(lv)化(hua)(hua)物(wu)，以及(ji)脂肪酸(suan)(suan)異(yi)丙(bing)(bing)(bing)(bing)(bing)酯和(he)(he)氯(lv)(lv)代(dai)脂肪酸(suan)(suan)異(yi)丙(bing)(bing)(bing)(bing)(bing)酯等。在精細(xi)化(hua)(hua)工方面，可用(yong)(yong)(yong)于生(sheng)(sheng)(sheng)產硝酸(suan)(suan)異(yi)丙(bing)(bing)(bing)(bing)(bing)酯，黃原酸(suan)(suan)異(yi)丙(bing)(bing)(bing)(bing)(bing)酯、亞磷酸(suan)(suan)三異(yi)丙(bing)(bing)(bing)(bing)(bing)酯、三異(yi)丙(bing)(bing)(bing)(bing)(bing)醇(chun)鋁(lv)以及(ji)醫(yi)藥和(he)(he)農藥等。作(zuo)(zuo)為溶(rong)劑(ji)(ji)，可用(yong)(yong)(yong)于生(sheng)(sheng)(sheng)產涂(tu)料、油(you)墨、萃(cui)(cui)(cui)取(qu)(qu)劑(ji)(ji)、氣(qi)溶(rong)膠(jiao)劑(ji)(ji)等。鹽城環(huan)保吡啶丙(bing)(bing)(bing)(bing)(bing)醇(chun)供應

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