凈化實驗室設計防靜電(dian)(dian)(dian)(dian)：所(suo)謂靜電(dian)(dian)(dian)(dian)，是(shi)由(you)于(yu)摩(mo)擦(ca)等原(yuan)因(yin)破(po)壞了物體中(zhong)正(+)負<一)電(dian)(dian)(dian)(dian)荷等量(liang)的(de)(de)均(jun)勻(yun)的(de)(de)電(dian)(dian)(dian)(dian)中(zhong)性狀態，而(er)使電(dian)(dian)(dian)(dian)荷過剩，物體呈帶電(dian)(dian)(dian)(dian)狀態，由(you)于(yu)這些電(dian)(dian)(dian)(dian)荷平時是(shi)不流動的(de)(de)，故稱靜電(dian)(dian)(dian)(dian)。1.靜電(dian)(dian)(dian)(dian)電(dian)(dian)(dian)(dian)引(yin)起的(de)(de)靜電(dian)(dian)(dian)(dian)電(dian)(dian)(dian)(dian)擊(ji)(ji)，引(yin)起人(ren)(ren)的(de)(de)不安全和(he)恐懼(ju)感(gan)，并可(ke)造(zao)成二次傷害(例如(ru)人(ren)(ren)因(yin)受電(dian)(dian)(dian)(dian)擊(ji)(ji)而(er)摔倒，由(you)摔倒又致(zhi)傷);2.靜電(dian)(dian)(dian)(dian)放(fang)電(dian)(dian)(dian)(dian)引(yin)起的(de)(de)放(fang)電(dian)(dian)(dian)(dian)電(dian)(dian)(dian)(dian)流，可(ke)導(dao)致(zhi)諸如(ru)半導(dao)體元件(jian)等破(po)壞和(he)誤動作，例如(ru)將(jiang)50塊P-MOS電(dian)(dian)(dian)(dian)路放(fang)在塑料袋內(nei)，搖晃數次后(hou)，與(yu)非門柵極嚴重(zhong)擊(ji)(ji)穿(chuan)者計39塊，失效率(lv)競(jing)達78%，這是(shi)因(yin)為半導(dao)體器件(jian)對靜電(dian)(dian)(dian)(dian)放(fang)電(dian)(dian)(dian)(dian)十(shi)分靈敏(min);3.靜電(dian)(dian)(dian)(dian)放(fang)電(dian)(dian)(dian)(dian)產生(sheng)的(de)(de)電(dian)(dian)(dian)(dian)磁波可(ke)導(dao)致(zhi)電(dian)(dian)(dian)(dian)子儀(yi)器和(he)裝置的(de)(de)雜音和(he)誤動作;4.靜電(dian)(dian)(dian)(dian)放(fang)電(dian)(dian)(dian)(dian)的(de)(de)發光可(ke)導(dao)致(zhi)照相(xiang)肢片等感(gan)光破(po)壞;5.靜電(dian)(dian)(dian)(dian)的(de)(de)力學(xue)現(xian)象可(ke)導(dao)致(zhi)篩孔被(bei)粉塵堵塞，紡紗線紛亂，印刷品深淺不均(jun)和(he)制品污(wu)染。選擇PCR實驗室的(de)(de)場地應(ying)避免繁華地段(duan)和(he)人(ren)(ren)流密集(ji)區(qu)域，應(ying)該盡(jin)可(ke)能選擇安靜、通風良好、通透性好的(de)(de)區(qu)域建設。廣東細胞培養GMP實驗室規劃

實(shi)(shi)驗中一(yi)旦(dan)發(fa)生了火(huo)(huo)(huo)(huo)災切不可(ke)(ke)驚慌失(shi)措，應(ying)保持(chi)鎮靜(jing)。首先立即(ji)切斷(duan)室內一(yi)切火(huo)(huo)(huo)(huo)源(yuan)和電源(yuan)。然后根據具體情況正確地進行搶救和滅(mie)火(huo)(huo)(huo)(huo)。常用(yong)(yong)的(de)(de)(de)方法有(you)：1.在(zai)可(ke)(ke)燃(ran)液體燃(ran)著(zhu)時(shi)(shi)(shi)，應(ying)立即(ji)拿開著(zhu)火(huo)(huo)(huo)(huo)區域內的(de)(de)(de)一(yi)切可(ke)(ke)燃(ran)物質，關閉通風(feng)器，防(fang)止擴大(da)(da)燃(ran)燒(shao)。若著(zhu)火(huo)(huo)(huo)(huo)面(mian)積較小，可(ke)(ke)用(yong)(yong)抹布(bu)、濕(shi)布(bu)、鐵片或(huo)沙土(tu)覆蓋，隔絕空氣(qi)使(shi)之熄(xi)滅(mie)。但覆蓋時(shi)(shi)(shi)要(yao)輕，避免(mian)碰壞或(huo)打(da)翻盛(sheng)有(you)易燃(ran)溶(rong)劑的(de)(de)(de)玻璃器皿，導致更多的(de)(de)(de)溶(rong)劑流出而(er)再著(zhu)火(huo)(huo)(huo)(huo)。2.酒精(jing)及他可(ke)(ke)溶(rong)于(yu)水(shui)的(de)(de)(de)液體著(zhu)火(huo)(huo)(huo)(huo)時(shi)(shi)(shi)，可(ke)(ke)用(yong)(yong)水(shui)滅(mie)火(huo)(huo)(huo)(huo)。3.汽油、甲苯等有(you)機溶(rong)劑著(zhu)火(huo)(huo)(huo)(huo)時(shi)(shi)(shi)，應(ying)用(yong)(yong)石棉布(bu)或(huo)砂(sha)土(tu)撲滅(mie)。千萬不能用(yong)(yong)水(shui)，否(fou)則(ze)反而(er)會(hui)擴大(da)(da)燃(ran)燒(shao)面(mian)積。4.金屬鈉著(zhu)火(huo)(huo)(huo)(huo)時(shi)(shi)(shi)，可(ke)(ke)把砂(sha)子倒在(zai)它的(de)(de)(de)上(shang)面(mian)。5.導線著(zhu)火(huo)(huo)(huo)(huo)時(shi)(shi)(shi)不能用(yong)(yong)水(shui)及二氧(yang)化(hua)碳(tan)滅(mie)火(huo)(huo)(huo)(huo)器，應(ying)切斷(duan)電源(yuan)或(huo)用(yong)(yong)四氯化(hua)碳(tan)滅(mie)火(huo)(huo)(huo)(huo)器。6.衣(yi)(yi)服燒(shao)著(zhu)時(shi)(shi)(shi)切忌(ji)奔走，可(ke)(ke)用(yong)(yong)衣(yi)(yi)服、大(da)(da)衣(yi)(yi)等包裹身體或(huo)躺在(zai)地上(shang)滾(gun)動，以滅(mie)火(huo)(huo)(huo)(huo)。7.發(fa)生火(huo)(huo)(huo)(huo)災時(shi)(shi)(shi)應(ying)注意保護(hu)現場。較大(da)(da)的(de)(de)(de)著(zhu)火(huo)(huo)(huo)(huo)事故應(ying)立即(ji)報(bao)警。東莞(guan)PCR實(shi)(shi)驗室凈(jing)化(hua)公司哪家(jia)好PCR實(shi)(shi)驗室是一(yi)種生物學實(shi)(shi)驗室，通常用(yong)(yong)于(yu)基因檢(jian)測和研究等領域。

實(shi)驗(yan)室(shi)的(de)(de)(de)(de)(de)管理(li)：1.人員(yuan)(yuan)管理(li)干(gan)細胞實(shi)驗(yan)室(shi)的(de)(de)(de)(de)(de)人員(yuan)(yuan)必(bi)須接受嚴格的(de)(de)(de)(de)(de)培(pei)訓和(he)考核，特(te)別(bie)是(shi)對(dui)于GMP的(de)(de)(de)(de)(de)管理(li)要求必(bi)須有充分的(de)(de)(de)(de)(de)認識和(he)執行，同時應該有責(ze)任心、敬業精神、協(xie)作(zuo)能力等職業素養。對(dui)于實(shi)驗(yan)室(shi)人員(yuan)(yuan)的(de)(de)(de)(de)(de)防護(hu)條件也應該嚴格把(ba)控。2.安(an)全(quan)管理(li)干(gan)細胞實(shi)驗(yan)室(shi)的(de)(de)(de)(de)(de)安(an)全(quan)管理(li)涉及到(dao)的(de)(de)(de)(de)(de)方面也非常多。操作(zuo)人員(yuan)(yuan)應該戴適當的(de)(de)(de)(de)(de)防護(hu)用品(pin)、消毒(du)設(she)備應用接受合適的(de)(de)(de)(de)(de)、科學的(de)(de)(de)(de)(de)消毒(du)處(chu)理(li)。3.物品(pin)管理(li)如何保證(zheng)實(shi)驗(yan)室(shi)耗材(cai)設(she)備等物品(pin)的(de)(de)(de)(de)(de)清潔、安(an)全(quan)也是(shi)實(shi)驗(yan)室(shi)重要的(de)(de)(de)(de)(de)工作(zuo)之(zhi)一(yi)。對(dui)于重要的(de)(de)(de)(de)(de)實(shi)驗(yan)樣品(pin)應該有相應的(de)(de)(de)(de)(de)保險(xian)措施。

防(fang)護實(shi)驗(yan)(yan)室(shi)——四級生(sheng)物(wu)安全研究水平(ping)：此級別需要處(chu)(chu)理危(wei)險(xian)且(qie)未知的(de)(de)(de)(de)病(bing)原體(ti)且(qie)該(gai)病(bing)原體(ti)可(ke)能造成經由氣(qi)溶(rong)膠傳(chuan)播之病(bing)原體(ti)或(huo)(huo)造成高(gao)度個(ge)人風(feng)險(xian)，且(qie)該(gai)病(bing)原體(ti)至今仍無任何已(yi)知的(de)(de)(de)(de)疫苗(miao)，如(ru)阿根廷出(chu)血熱與(yu)剛果(guo)(guo)出(chu)血熱、埃博拉(la)病(bing)毒(du)，馬爾(er)堡病(bing)毒(du)，拉(la)薩熱，克(ke)里米(mi)亞-剛果(guo)(guo)出(chu)血熱，天花，以及其(qi)他各種出(chu)血性(xing)(xing)疾病(bing)。當(dang)處(chu)(chu)理這類(lei)(lei)生(sheng)物(wu)危(wei)害病(bing)原體(ti)時必(bi)(bi)須且(qie)具強(qiang)制性(xing)(xing)地使(shi)用供(gong)氧的(de)(de)(de)(de)正壓防(fang)護衣。生(sheng)物(wu)實(shi)驗(yan)(yan)室(shi)的(de)(de)(de)(de)四個(ge)出(chu)入(ru)口將配置多(duo)個(ge)淋浴設備、真空室(shi)與(yu)紫(zi)外線光(guang)室(shi)，及其(qi)他旨在摧毀(hui)所有的(de)(de)(de)(de)生(sheng)物(wu)危(wei)害的(de)(de)(de)(de)痕跡安全防(fang)范(fan)措施(shi)。多(duo)個(ge)氣(qi)密鎖將被廣(guang)泛應用并被電子(zi)保(bao)護以防(fang)止在同一(yi)時間(jian)打開兩個(ge)門。所有的(de)(de)(de)(de)空氣(qi)和(he)水的(de)(de)(de)(de)服務(wu)，將和(he)來(lai)自(zi)生(sheng)物(wu)安全4級（或(huo)(huo)P4）實(shi)驗(yan)(yan)室(shi)將進行(xing)類(lei)(lei)似的(de)(de)(de)(de)消毒(du)程序(xu)，以消除意(yi)外釋放的(de)(de)(de)(de)可(ke)能性(xing)(xing)。當(dang)一(yi)個(ge)病(bing)原體(ti)被懷疑(yi)或(huo)(huo)可(ke)能有抗藥性(xing)(xing)時都必(bi)(bi)須在BSL-4實(shi)驗(yan)(yan)室(shi)進行(xing)處(chu)(chu)理，直到有足(zu)夠的(de)(de)(de)(de)數據得(de)到確認(ren)必(bi)(bi)須在此規格實(shi)驗(yan)(yan)室(shi)持(chi)續(xu)工作，或(huo)(huo)移(yi)交至一(yi)個(ge)較低水平(ping)的(de)(de)(de)(de)實(shi)驗(yan)(yan)室(shi)。細胞培養實(shi)驗(yan)(yan)室(shi)由無菌(jun)操作區(qu)(qu)、孵育區(qu)(qu)、制備區(qu)(qu)、儲(chu)藏區(qu)(qu)、清洗和(he)消毒(du)滅菌(jun)區(qu)(qu)6部(bu)分(fen)組成。

CAR-T細胞建(jian)設：工作操作的(de)(de)要求1.CAR-T細胞制劑的(de)(de)制備應當(dang)按照(zhao)經過(guo)驗(yan)(yan)證(zheng)后(hou)批準(zhun)的(de)(de)操作規程的(de)(de)要求進(jin)行，并有(you)相關記錄，以確保CAR-T細胞制劑達到規定的(de)(de)質(zhi)量標(biao)(biao)準(zhun)。2.在樣本操作區(qu)以及病毒(du)的(de)(de)制備區(qu)內，操作人員應當(dang)穿戴(dai)該(gai)區(qu)域使(shi)用的(de)(de)防(fang)護服。3.同一個(ge)培(pei)養(yang)箱內不(bu)得同時存放兩(liang)個(ge)不(bu)同批次的(de)(de)細胞培(pei)養(yang)產(chan)品，以免混淆造成嚴重后(hou)果。應在細胞培(pei)養(yang)耗材及培(pei)養(yang)箱上進(jin)行標(biao)(biao)識。深(shen)圳市勵康凈(jing)化(hua)工程有(you)限公司是一家(jia)專(zhuan)注于無(wu)塵車(che)間(jian)、GMP車(che)間(jian)、生(sheng)物潔(jie)凈(jing)室、實(shi)驗(yan)(yan)室等工程和(he)中央空調工程的(de)(de)設計、安裝的(de)(de)專(zhuan)業公司，從生(sheng)產(chan)工藝平(ping)面布(bu)局到車(che)間(jian)裝修(xiu)(xiu)、暖通(tong)、電氣、工藝管道、給排水等，為潔(jie)凈(jing)室裝修(xiu)(xiu)及相關機(ji)電安裝工程領域服務。實(shi)驗(yan)(yan)室家(jia)具應該(gai)是耐用、易于清(qing)潔(jie)、抗腐蝕和(he)有(you)助于工作效率的(de)(de)功能性家(jia)具。南山區(qu)NK細胞實(shi)驗(yan)(yan)室設計

生物(wu)(wu)安(an)全實(shi)驗室，也就(jiu)是生物(wu)(wu)實(shi)驗室，是進行與生物(wu)(wu)科相關的(de)實(shi)驗的(de)場(chang)所(suo)。廣東細胞培養GMP實(shi)驗室規劃

基因測(ce)序實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)設(she)(she)(she)計(ji)遵循16字方針——分區明確、因地(di)制宜、方便(bian)使用。1、“分區明確”：指各(ge)實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)在(zai)物理格局(ju)和空間使用上彼此互(hu)不(bu)(bu)干擾，包括實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)各(ge)區的(de)(de)儀器設(she)(she)(she)備(bei)、清潔用具等(deng)；2、“因地(di)制宜”：指實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)各(ge)區既(ji)可(ke)(ke)相互(hu)臨近，可(ke)(ke)以設(she)(she)(she)計(ji)在(zai)同(tong)樓(lou)層的(de)(de)不(bu)(bu)同(tong)地(di)方，也可(ke)(ke)以設(she)(she)(she)計(ji)在(zai)不(bu)(bu)同(tong)的(de)(de)樓(lou)層；3、“方便(bian)使用”：指實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)設(she)(she)(she)計(ji)時，既(ji)要(yao)考慮實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)現(xian)有場地(di)的(de)(de)實(shi)(shi)(shi)(shi)(shi)(shi)際情況，同(tong)時考慮實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)人員(yuan)在(zai)檢測(ce)過程(cheng)中(zhong)的(de)(de)舒適(shi)性和方便(bian)性。此外，實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)設(she)(she)(she)計(ji)原則必須滿足擬開(kai)展(zhan)檢測(ce)項目的(de)(de)工藝流(liu)程(cheng)要(yao)求以及(ji)檢測(ce)平(ping)臺(tai)對環境的(de)(de)要(yao)求，包括實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)分區數(shu)量(liang)、面積、溫(wen)濕(shi)度、承重(zhong)、電壓等(deng)要(yao)求。實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)平(ping)面設(she)(she)(she)計(ji)完成后，還需(xu)整合(he)實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)場地(di)勘(kan)察概況、實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)設(she)(she)(she)計(ji)平(ping)面圖、實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)各(ge)專業(給(gei)排水、強電、弱電、暖通、裝飾)參數(shu)表、擬開(kai)展(zhan)項目工藝流(liu)程(cheng)圖、實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)平(ping)面設(she)(she)(she)計(ji)確認表和實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)設(she)(she)(she)計(ji)標(biao)準，形成遵守國(guo)家規(gui)定(ding)、符(fu)合(he)臨床需(xu)求、可(ke)(ke)實(shi)(shi)(shi)(shi)(shi)(shi)施的(de)(de)設(she)(she)(she)計(ji)方案。廣東(dong)細胞培養GMP實(shi)(shi)(shi)(shi)(shi)(shi)驗(yan)(yan)(yan)(yan)(yan)室(shi)規(gui)劃(hua)

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